Thirupathi (Vadivelu), Ezhumalai (S. Ve. Shekher) and Venkatesa (Prabhu) are poor friends who tried to become rich. Nachiappan (Venniradai Moorthy), a bungalow watchman, has three daughters : Lalitha (Kovai Sarala), Padmini (Urvashi) and Ragini (Roja). When his owner left the bungalow on vacation, Nachiappan's daughters decide to live there. Then, Nachiappan rents his owner's top portion bungalow to Thirupathi, Ezhumalai and Venkatesa who lied about their job.

A young woman falls in love with a man and wishes to marry him. However, everything changes when she learns about her father's involvement in his first wife's death.

Venkata Ramana (Venkatesh) is a ventriloquist. He goes along with the troop of artists to perform for a local Telugu association in Europe. Paris Prasad (Brahmanandam) is a tour organizer in Europe. He enjoys making people around bakras. Pooja (Trisha) is the niece of Prasad. Venkata Ramana falls in love with her. Prasad realises that only way to make Ramana bakra is to tell him that Pooja loves him too. Pooja is the daughter of a rich factionist in Rayalaseema and she is forced to return back in the middle. Her marriage is fixed with a guy she doesn’t like. The rest of the story is all about how Prasad conspires with Ramana to rescue Pooja.

Thirupathi Express' is a clean fun-filled family entertainer, starring Sumanth Shailendra and Kriti Kharbanda in the lead roles. . The film is a travel love story. The family of Sumanth is bound to Tirupathi, while on the journey he meets many characters, turning out to be a roller coaster ride of adventure. What happens when he misses the train, forms the crux of the story.

Thirupathi Express' is a clean fun-filled family entertainer, starring Sumanth Shailendra and Kriti Kharbanda in the lead roles. . The film is a travel love story. The family of Sumanth is bound to Tirupathi, while on the journey he meets many characters, turning out to be a roller coaster ride of adventure. What happens when he misses the train, forms the crux of the story.

Three sisters are obsessed with money and dream to marry wealthy grooms. They marry three prospective grooms but later learn that they are ordinary people and refuse to live with them.